Omics Technologies

Studiengang

Masterstudiengang Biotechnologie

Kennzahl der Lehrveranstaltung

BT_MA20_3_2

Anzahl der zugewiesenen ECTS-Credits

3.0

Name des/der Vortragenden

Dr. Weinberger Klaus

Art der Veranstaltung

face-to-face

empfohlene optionale Programmeinheiten

Derzeit nur in Englisch verfügbar
none

empfohlene Fachliteratur

Derzeit nur in Englisch verfügbar
Lesk AM. Introduction to genomics. Oxford University Press 2017
Passos GA. Transcriptomics in health and disease. Springer 2014
Wyatt P. Proteomics - Principles, techniques, and analysis. Syrawood 2018
Sussulini A. Metabolomics: From fundamentals to clinical applications. Springer 2017
Voit EO. A first course in systems biology. Garland Science 2017

Prüfungsmethode

Course immanent examination

Niveau der Lehrveranstaltung laut Lehrplan

Master

Studienjahr

Fall 2025

Semester in dem die Lehrveranstaltung angeboten wird

3

Unterrichtssprache

English

Lernergebnisse der Lehrveranstaltung

Derzeit nur in Englisch verfügbar
In this course, students are familiarised with multiplexed bioanalytical platforms, the so-called omics technologies, the biostatistics and bioinformatics tools needed for managing and analysing the data sets, and the impact of the results on biomarker development and validation. To this end, the course will cover the four major platforms, i.e. genomics, transcriptomics, proteomics, and metabolomics, and evaluate their completeness, standardisation, the qualitative or quantitative nature of the data, the functional annotation of the analytes and, eventually, their relevance for pathobiochemical insights and diagnostic/prognostic tests.

Lehrinhalte

Derzeit nur in Englisch verfügbar
- Omics technologies and information flow in systems biology
- Genomics (with a special focus on genetic variability in humans)
- Transcriptomics (array and NGS-based approaches, data visualisation and interpretation)
- Analytical platforms and workflows for proteins and metabolites (NMR, MS)
- Proteomics (top-down and bottom-up, identification and quantitation)
- Metabolomics (targeted and non-targeted, identification and quantitation)
- Biomarker discovery and validation, quality criteria, multi-omics approaches

Lehr- und Lernformen

Derzeit nur in Englisch verfügbar
Lecture accompanied by problem-oriented discussions and student's presentations

Praktikum

none

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