Biological process engineering

Department

Bachelor's program Environmental, Process & Energy Engineering

Course unit code

UVET_BA_5_5

Number of ECTS credits allocated

3.0

Name of lecturer(s)

Dr. Margreiter Gerd, Dr. nat. techn. Dumfort Sabrina, BSc MSc

Mode of delivery

face-to-face

Recommended optional program components

none

Recommended or required reading

Pauline Doran: Bioprocess Engineering Principles 2nd Edition; Academic Press (2013) ISBN 978-0-12-220851-5
Horst Chmiel: Bioprozesstechnik 4. Auflage; Springer Spectrum (2018) ISBN 978-3-662-54041-1
Georg Fuchs, Hans-Günter Schlegel: Allgemeine Mikrobiologie 10. Auflage, Thieme Verlag (2017) ISBN 978-3132418851
Sven-Olof Enfors and Lena Häggström: Bioprocess Technology Fundamentals and Applications; Högskoletryckeriet, Royal Institute of Technology, Stockholm (2000) ISBN 91-7170-511-2
R.D. Schmid: Pocket Guide to Biotechnology and Genetic Engineering; Wiley-VCH (2003) ISBN 3-527-30895-4
Storhas, W.: Bioverfahrensentwicklung, Wiley-VCH, 2006
Storhas, W.: Bioreaktoren und periphere Einrichtungen, Vieweg, 1994
Hass V.C. und Pörtner R.: Praxis der Bioprozesstechnik, Spektrum Akademischer Verlag, 2011Günter Jagschies et al: Biopharmaceutical Processing: Development, Design and Implementation of Manufacturing Processes; Elsevier (2018) ISBN 978-0-08-100623-8
Karl-Erich Jaeger, Andreas Liese, Christoph Syldatk: Einführung in die Enyzmtechnologie 1st ed., Springer Spectrum (2019) ISBN 978-3-662-57618-2
Hansjörg Wagner: Mammalian Cell Biotechnology in Protein Production; De Gruyter (1997) ISBN 978-3-11-013403-2

Level of course unit

Bachelor

Year of study

Fall 2025

Semester when the course unit is delivered

5

Language of instruction

English

Learning outcomes of the course unit

Students are able to apply the methods of mechanical, chemical and thermal process engineering to biological processes used for technical purposes. They know the underlying specifics of biochemical processes for drawing mass and energy balances and are able to link them to knowledge of mathematical elaboration of mass and heat balances.
Students understand the specifics to apply process engineering principles for biological reactions.

Course contents

• Presentation of technically relevant microorganisms and cells, their substrate requirements and development conditions, models of enzyme kinetics, growth kinetics of microorganisms and kinetics of product formation
• Realisation of such requirements by primary tasks (homogenisation, suspension, dispersion, mass and heat transfer) of a bioreactor
• Identification of bioreactors by type, fittings, measurement and control units as well as behaviour over time
• Balance of processes at the bioreactor
• Secondary tasks of a bioreactor (e.g. sterilisation processes) as well as first considerations in terms of scaling up

Planned learning activities and teaching methods

The course comprises an interactive mix of lectures, discussions and individual and group work.

Work placement(s)

none